Description
Product Characteristics: Synonyms: GPR178, KIAA1423
Mediates action of cytolethal distending toxins(CDT), which are secreted by many pathogenic bacteria. Expression level of TMEM181 is rate-limiting for intoxication.
Target Information: The TMEM181 gene encodes a putative G protein-coupled receptor expressed on the cell surface (Carette et al., 2009 [PubMed 19965467]\\\\, Wollscheid et al., 2009 [PubMed 19349973]).[supplied by OMIM, Jan 2010]